The wizard shows off her disintegrate spell in this piece of artwork from Blizzard's official Diablo 3 character page. The four-armed goatman behind her is not a creature that's been seen in any other artwork, though it's very similar in overall appearance and even in pose to this piece of Goatman concept art.

Compare to the larger version of this image, seen in the Blizzard Gallery at their Irvine Campus.

Artwork by Josh Tallman.