It's cute you think they left choices, lol. Your spec can make a huge difference too. If it's not str and vit and res all, it's probably not itemized so you can really use it.
Don't be surprised if progressing becomes a matter of switching to sword and board to start a new act until you get significant upgrades, then going back 2 handers to contiue farming upgrades just to go back to sword and board to finally start the next act.
Im reading all this and im wondering about how i can handle 2-3 champion packs at once with my WD, which got 100-300 res, 75k hp, 17k dps unbuffed and 201% MF? ( Yea, i got MF gear, farming act II since few weeks )
Well it doesn't matter for effective hp if you double your res or your hp, it's the same result. You got so many hp that you can survive even with low resists.
But it's not as effective in respect to healing the less hitpoints you have the more effectively you can recover once you were hit. Healing 75k life is difficult, pots are almost useless at this point and any other ways are also 1/2 to 1/3 as effective.