I was watching some videos and got a bit worried about some monster combos that would be tricky to deal with by just jumping into the fray (lightning enchanted - stuff like that). Also, I was looking for a way to combine a 2H-build with some good synergies and came up with the build below.
The build can be used with both 2h mighty (+fury, which may be more relevant before "unforgiving" at 55), swords (+%dmg) and polearms/spear. No particular focus on crit, more in the line of straight damage and fury + revenge procs. 1h + shield is also an option, though the build is focused around the high/slow damage of 2-handers.
The general idea is to use cleave as a standard attack and fury generator. To make the best of the reaping swing rune, ancient spear + grappling hooks are use to get a positioned cluster of enemies, so cleave should be hitting 3 mobs most of the time. Hammer of the Ancients is used as a fury spender, combined with revenge when available and battle rage when possible.
Using ancient spear with grappling hooks should enable the option of "sniping" mobs or as an alternative use harpoon and target key mobs to kill.
Leap is used as a secondary mobility tool with iron impact at first and later possibly call of arreat (again, to cluster enemies and maximize efficiency of hammer of the ancients).
Mid-level build (req 30): http://eu.battle.net/d3/en/calculato...dVi!ZYX!ZZaaaa
The final build (req 55): http://eu.battle.net/d3/en/calculato...dVi!hYg!ZZYaca (updated with brawler, thanks Elemental)
Unforgiving at 55 changes the dynamic a bit, since front loading becomes a more reliable option. Call of arreat at 44 might also affect the dynamic, since it has the potential to proc revenge a lot. At the moment revenge looks pretty overpowered, I'll wager the proc chance gets heavily reduced soon :-)
Defense is adressed mostly through revenge and inspiring presence which may be too weak at late hell level / inferno difficulty. In that case inspiring presence, could be to swapped for either tough as nails or nerves of steel. Another option is to swap in a shield and go 1h mighty or swords.