a few points Gandalf....
1: your minimum damage is 1/3'rd of mine (i have 100% deadly strike), so your 7k vs my 22k (before factoring in PvP penalties etc)
2: because you dumped so much into strength, you have ~500 less life than me (which would blow out to well over 1k if i had top end charms on my charger, which i don't)
3: i'll grant you that the -25% target defence is a very nice mod to have.
4: not everyone is prepared to use duped runes. an e-Death requires merely 3x Gul runes while finding or cubing up a Zod rune is either unlikely (finding) or painful (cubing).
5: you havn't factored in Crushing Blow damage. an e-Death build will probably hit 100% CB, while an ebotd build won't. CB on that first hit is a very nice wodge of damage against high life opponents like Druids and Hammerdins.
all that said, yes you can most definatly get One Hit Kills with an eBotD thunder maul or war pike.
both will work. i just prefer the e-Death. it's a lot cheaper (which fits the theme of my build perfectly. i threw it together from scraps i had gathering e-Dust on mules)
edit: here is an example of where 2h chargers really excel: taking out auto-tp, hacked up the wazoo hammerdins.
seeing as i have never used any form of hack in my life (and never will), i really enjoy instagibbing the BM hacktards that seem to infest battlenet.
while we're on the topic, TC-Ogre from that game volunteered for a little damage testing. 7.3k PvP damage good enough for yah? after these, he put some more %DR on and my best hit was still over 5.5k.